April 12, 2024 – Scientists and researchers have long caused concern about the potential increased risk of autism and ADHD Taking acetaminophen during pregnancy F.D.A. And that American College of Obstetricians and Gynecologists It is said to be safe to use even with children.
But the new discovery should bring relief to pregnant people who need pain relief. full aspirin and non-steroidal anti-inflammatory drugs It has been shown to pose a serious risk to pregnant patients.
Taking over-the-counter painkillers containing acetaminophen, such as Tylenol, during pregnancy does not increase the child's risk of developing autism, attention-deficit/hyperactivity disorder (ADHD), or intellectual disability. This was discovered in a large-scale study.
Jeffrey Klar, M.D., a maternal-fetal medicine specialist at Duke University, says that when a pregnancy has an abnormal outcome, patients are often quick to blame themselves, recalling every moment that could have gone wrong during the pregnancy. I will explain that it will happen.
„Recall bias is real,“ said Klar, who was not involved in the study. „I feel guilty. 'Did I cause this? Was it because of the cigarettes and drinks I smoked before I knew I was pregnant?'
In reality, when a child has autism, ADHD, or a learning disability, the causes are usually varied, but it's still unclear why some children have such problems with brain development. Not fully understood.
„I think it's pretty unlikely that Tylenol someone took during pregnancy would have caused such an outcome,“ Klar said. “This is a huge scope and a way to make people who are already feeling sick in a difficult situation even worse.”
The study was led by researchers at Sweden's Drexel University and Karolinska Institutet and was published this week. of American Medical Association Journalanalyzed medical record data for approximately 2.5 million children born in Sweden between 1995 and 2019.
The results showed that children who were exposed to acetaminophen during pregnancy were at slightly increased risk for autism, ADHD, and learning disabilities when compared to those who were not. However, when we expanded the data to include complete sibling pairs (sibling pairs born to the same biological parents), we found no evidence linking Tylenol to a higher risk of autism, ADHD, or learning disabilities. did.
The use of sibling analysis in large-scale studies such as this reveals previously unseen genetic and environmental factors. The authors suggest that if sibling control is not taken into account, the modest association between Tylenol use during pregnancy and autism, ADHD, and learning disabilities may be passed down through genes that cause developmental problems. „People who used acetaminophen during pregnancy reported higher rates.'' “Compared with non-users, there is a higher prevalence of multiple health conditions associated with neurodevelopmental disorders,” they wrote.